We develop microtechnologies for small-scale electromechanical & mechanobiology measurements to study how mechanics mediates biological signaling. For example, we study signaling, and mechanisms and forces of cell adhesion in coordinating cell behavior and response to mechanical changes, as well as the development and response of stem cells and cardiac myocytes to mechanical loading. We design and fabricate most of our own tools and sensors and are interested in the reliable manufacture and operation of micromachined sensors and actuators in harsh environments, measuring nanoscale mechanical behavior, and the analysis, design, and control of integrated electro-mechanical systems. We leverage new tools and answer novel questions in our lab in the areas of physiology, biology, stem cells, neuroscience, and cardiology with an eye toward quantitative and fundamental biophysics.